Floyd E. Romesberg

A Semi-synthetic organism that stores and retrieves increased genetic information
Synthorx, Inc., USA


Floyd E. Romesberg received a B.S. and M.S. in chemistry from The Ohio State University, and a PhD in physical organic chemistry from Cornell University. He was an NIH postdoctoral fellow at UC Berkeley with Peter Schultz, and in 1998 joined the faculty at The Scripps Research Institute until 2019. Romesberg’s research laboratory applies organic chemistry, microbiology, non-linear optical spectroscopy, and genetics, to study different aspects of evolution. Of particular significance is his work to expand the genetic alphabet and code through the development of a third DNA base pair that relies on hydrophobicity as opposed to hydrogen bonding for selective pairing.

Romesberg has been recognized by several awards including the Camille Dreyfus Teacher Scholar Award, the NSF CAREER Award, the Discover Magazine Technology Innovation Award, the ACS Nobel Laureate Signature Award, and the Royal Society of Chemistry’s 2018 Bioorganic Chemistry Award. His research has been funded by NIH, NSF, Office of Naval Research, and Defense Advanced Research Projects Agency. Romesberg is also a scientific founder of several biotech companies, including Achaogen, Inc., RQx Inc., and Synthorx, Inc.